Bacteriophage-Fused Peptides for Serodiagnosis of Human Strongyloidiasis
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چکیده
منابع مشابه
Bacteriophage-Fused Peptides for Serodiagnosis of Human Strongyloidiasis
BACKGROUND Strongyloidiasis, a human intestinal infection caused by the nematode Strongyloides stercoralis, is frequently underdiagnosed and although its high prevalence is still a neglected parasitic disease because conventional diagnostic tests based on parasitological examination (presence of Strongyloides larvae in stool) are not sufficiently sensitive due to the low parasitic load and to t...
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The sensitivity specificity of an enzyme-linked immunosorbent assay (ELISA) for the serodiagnosis of strongyloidiasis has been investigated. 45 men with long-standing strongyloidiasis were compared with the same number of age- and sex-matched control subjects. The ELISA detected antibody in 84% of patients with parasitologically proven strongyloidiasis. When the technique was compared with an i...
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Strongyloidiasis caused by intestinal nematode Strongyloides stercoralis may leads to hyperinfection syndrome and disseminated infections. If not diagnosed and treated properly, it may even end to the death of patients. Sensitivity of parasitological methods is not good enough and multiple stool sampling over consecutive days is essential to improve the detection rate. The agar plate culture me...
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ژورنال
عنوان ژورنال: PLoS Neglected Tropical Diseases
سال: 2014
ISSN: 1935-2735
DOI: 10.1371/journal.pntd.0002792